In this reboot of the Three Paper Thursdays, back after a hiatus of almost eight years, I consider the many different ways in which programs can be sanitised to detect, or mitigated to prevent the use of, the many programmer errors that can introduce security vulerabilities in low-level languages such as C and C++. We first look at a new binary translation technique, before covering the many compiler techniques in the literature, and finally finishing off with my own hardware analysis architecture.